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Desmond T. Quek, Sang Beom Han, Tina Wong, Donald Tan, Jodhbir Mehta; Graft Failure And Intraocular Pressure Control After Keratoplasty In Iridocorneal Endothelial Syndrome. Invest. Ophthalmol. Vis. Sci. 2012;53(14):6049.
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© ARVO (1962-2015); The Authors (2016-present)
To describe the outcomes, and intraocular pressure (IOP) control after keratoplasty (KP) in eyes with iridocorneal endothelial (ICE) syndrome.
Retrospective review of all eyes with ICE syndrome that underwent KP between 1997-2010. Main outcome measures were graft failure and post-KP IOP. Variables examined included demographics, pre-KP IOP, post-KP IOP indices (maximum, minimum, mean and range of IOP), pre- and post-KP glaucoma treatment, duration of follow-up, intraoperative complications and post-KP visual acuity (VA).
Fifteen eyes (mean age 55.6±10.4, 66.7% female) underwent KP with a mean follow-up of 6.3 years. 73% were penetrating KP (PK) while 27% were descemets stripping automated endothelial KP (DSAEK). There were no intraoperative complications. 33% (5/15) of grafts failed after a mean of 4.3±3.8 years - 4 (80%) were PK while 1 (25%) was DSAEK. The mean IOP increased from 14.9 mmHg to 16.6 mmHg post-KP (p=0.10). Grafts that failed had lower pre-KP IOP compared to those that did not (12.4 vs 16.2 mmHg, p=0.03). There were no differences in demographics, follow-up duration, type of KP, glaucoma treatment pre- and post-KP and IOP indices between grafts that failed and those that did not.
A third of grafts failed after KP for ICE syndrome. IOP did not increase significantly post KP. Both PK and DSAEK had similar outcomes with regards to graft failure and IOP control.
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