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Salima I. Hassanaly, Julia Talajic, Mona Harissi-Dagher; Outcomes following Boston Keratoprosthesis Type I Implantation in Aniridia Patients: The University of Montreal Experience. Invest. Ophthalmol. Vis. Sci. 2012;53(14):6066.
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© ARVO (1962-2015); The Authors (2016-present)
To describe outcomes after Boston Keratoprosthesis Type 1 (KPro) surgery in aniridic eyes.
A retrospective chart review of 21 aniridic eyes (15 patients) that underwent KPro implantation by a single surgeon (MHD) between October 2008 and April 2011 in a university center was performed. Preoperative and postoperative best-corrected visual acuity (BCVA), intraoperative and postoperative complications, and keratoprosthesis retention were examined.
Mean age was 54.3 years (range, 27-71); 8 patients were male. Six patients had bilateral procedures. No intraoperative complications were encountered. Preoperatively, BCVA was 20/200 or worse in all eyes. After a mean follow-up time of 20.9 months (range, 4.2-36.2), the most recent BCVA ranged from 20/70 to no light perception. Visual potential was limited by pre-existing terminal glaucoma (n=2), phthisis after retinal detachment (n=2), and suprachoroidal hemorrhage (n=2). Other postoperative complications included retroprosthetic membrane formation (n=11), trans-prosthetic leakage (n=2), and extrusion (n=1). Uncomplicated uveitis was reported in 6 eyes. No endophthalmitis or corneal melt occurred in this series. The majority of eyes have glaucoma and are on medical treatment.
The prognosis in aniridic patients after KPro is variable, but is favorable overall. Meticulous follow-up and a subspecialty team approach are important.
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