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Ana Prinz, Birgit Weingessel, Oliver Findl, Pia V. Vecsei-Marlovits; Posterior Capsule Opacification of a 1-piece and a 3-piece Microincision Intraocular Lens - 1 year Comparison. Invest. Ophthalmol. Vis. Sci. 2012;53(14):6623.
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The aim of this study was to compare the intensity of posterior capsular opacification (PCO) between the 1-piece and 3-piece haptic designs of the hydrophobic microincision intraocular lens (MICS IOL) 1 year after cataract surgery.
This randomized, prospective, patient and examiner masked clinical trial comprised 80 eyes of 40 patients with age-related cataract. Each patient underwent cataract surgery in both eyes and received a 1-piece MICS IOL (Hoya AF-1iMics NY-60, Hoya, Japan) in one eye and a 3-piece MICS IOL (Hoya AF-1iMics Y-60H, Hoya, Japan) in the other eye. At year 1 follow-up, the patients were examined at the slit lamp, visual acuity (VA) was determined and standardized high-resolution digital retroillumination images were taken for objective quantification of regeneratory PCO. The intensity of fibrotic PCO was assessed subjectively at the slit-lamp (scale 0-3) and the amount of regeneratory PCO (score range 0-10) was assessed objectively using automated image analysis software (AQUA).
There was no significant difference between IOL styles in best-corrected VA, rhexis/IOL overlap, decentration of the IOL and amount of fibrotic PCO. Capsular folds occurred significantly more often in the 3-piece IOL group (1-piece, 9 cases, 3-piece, 18 cases; P = 0.01). The mean regeneratory PCO score was 0.3 in both IOL groups (P = 0.6). The Nd:YAG laser capsulotomy rate was slightly higher in the 3-piece group (2 cases vs. 1 at 1 year; P = 0.2).
Modification of the MICS IOL from a 3-piece to a 1-piece open-loop haptic design caused no significant change in PCO amount and neodymium:yttrium-aluminium-garnet laser treatment rate. Compared with the 3-piece IOL, the 1-piece IOL led to significantly less capsular folds one year after surgery.
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