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Erin M. Scott, Douglas W. Esson, Kevin J. Fritz, Richard R. Dubielzig; Major Breed Distribution and Common Histopathologic Findings in Canine Globes Enucleated as a Result of Glaucoma Following Cataract Surgery. Invest. Ophthalmol. Vis. Sci. 2012;53(14):6627.
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© ARVO (1962-2015); The Authors (2016-present)
To identify the most significantly represented breeds and to describe the major histopathological features of canine globes enucleated due to glaucoma following cataract surgery.
Retrospective review of the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) database revealed 153 canine globes that met inclusion criteria. The most commonly affected breeds were identified. Following standard hematoxylin & eosin staining, the globes were histopathologically evaluated for the presence of corneal findings, goniodysgenesis, pigment dispersion, fibrovascular membrane formation, inflammatory infiltrates, lens capsule pathology, retinal detachment and/or bacterial endophthalmitis.
The most significantly represented breeds were the Cocker Spaniel (11.7%), Boston Terrier (9.8%), Labrador Retriever (6.5%), Bichon Frise (6.5%), Jack Russell Terrier (5.8%) and Shih Tzu (5.8%).
The Cocker Spaniel, Boston Terrier, Labrador Retriever, Bichon Frise, Jack Russell Terrier and Shih Tzu may be at increased risk for the development of glaucoma following elective cataract surgery. Common histopathologic findings included inflammatory keratitis, the presence of pre-iridal fibrovascular membranes, and lymphoplasmacytic uveal infiltrates. These findings have potential clinical implications.
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