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Vasile Diaconu, Patrick Sauvageau, Valentina Vucea; Optic Nerve Head Capillaries Blood Oxygenation Following Dynamic Exercise in Human. Invest. Ophthalmol. Vis. Sci. 2012;53(14):6864.
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It is generally suggested that the blood flow in the human eye retinal vessels can be regulated to satisfy the metabolic requirements. This physiological process called auto-regulation is engaged to maintain a relatively constant ocular blood flow (OBF) to compensate for changes in the ocular perfusion pressure (OPP). The goal of the present study was to investigate the blood oxygenation of the optical nerve capillaries, in function of the OPP changes, after dynamic exercise.
Six healthy non-smoking men (mean age: 22; range: 20-25 years) have participated in the study. A high level physical effort has been generated by using the computerized stationary bicycle. The pulse rate (PR) of 160 beats per minute has been always reached after a session of 15 minutes of exercise for each subject. The blood oxygenation of the optic nerve’s capillaries (BOONH) has been derived by the multichannel spectroscopy technique (Vucea et al., 2011). The BOONH, brachial blood pressure (Bp), intraocular pressure (IOP) and systemic arterial blood oxygenation have been evaluated in each subject before and after the exercise session.
The results demonstrate the correlations between the IOP and BOONH variations for each subject, R2=0,98. These correlations indicate that following an intense physical exercise the subjects who have demonstrated an important reduction in IOP also have experienced an important reduction in BOONH (i.e. blood flow).
The results of the present study are in agreement with previous studies (Stefansson et al., 2005) which explain that the optic nerve’s blood oxygenation is regulated by the IOP, the mean arterial blood pressure and the retinal blood vessels resistance.
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