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M. Haque, B. A. Hughes, M. S. Juzych, A. Goyal, M. Y. Alexander, S. Wolfe, C. Kim; The Effect of Selective Laser Trabeculoplasty (SLT) With Heavy versus Light Pigmentation of the Trabecular Meshwork (TM). Invest. Ophthalmol. Vis. Sci. 2009;50(13):161.
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To compare the effect of Selective Laser Trabeculoplasty (SLT) in reducing intraocular pressure (IOP) in patients with light, moderate, or heavy pigmentation of the trabecular meshwork (TM).
This is a retrospective chart review of 83 eyes of 77 patients with open angle glaucoma (OAG) who underwent SLT from November 2006 to June 2008 for inadequately controlled IOP. Six patients underwent SLT in both eyes. Patients undergoing SLT for retreatment were excluded from analysis. Patients were assessed at time of SLT and classified as having light (Group I), moderate (Group II), or heavily (Group III) pigmented TM by gonioscopy. Post-SLT IOP’s were followed for an average of 5.3 ± 4.1 months. Demographic data were evaluated using chi-square and ANOVA tests. Mean IOP reduction was evaluated in each group using paired sample t-test. IOP reduction between the three groups was compared using the ANOVA test.
Of the 83 eyes, 28 eyes were in Group I, 39 eyes in Group II and 16 eyes in Group III. Demographics for all 3 groups were comparable with respect to age, race, and sex (p > 0.1). The mean pre-SLT IOP was 22.1 (± 4.3) mm Hg in Group I, 22.2 (± 4.5) mm Hg in Group II, and 22.8 (± 4.4) mm Hg in Group III. Baseline pre-SLT IOP among all 3 groups showed no statistical difference (p = 0.9). The mean post-SLT IOP reduction was 4.0 (± 3.9) mm Hg in Group I, 5.1 (± 5.7) mm Hg in Group II, and 4.1 (± 4.2) mm Hg in Group III. There was a significant IOP reduction in all 3 groups (p < 0.005) but there was no difference in magnitude between the three groups (p = 0.65).
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