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J. A. Cardillo, A. Daré, R. Peroni, D. Lavinsky, R. A. Costa, C. E. Moreira; Optimal Endpoint and Lesion Character for Subtreshold Micropulse Photocoagulation Protocols Targeting Diabetic Macular Edema. Invest. Ophthalmol. Vis. Sci. 2009;50(13):217.
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To clinically compare the characteristics of the retinal lesions of successfully and non-successfully treated patients that underwent subthreshold 810nm-diode micropulse (SDMP) photocoagulation for diabetic macular edema.
A retrospective clinical and angiographic analysis of the resulting macular coagulation lesions of 200 eyes that underwent SDMP was performed. Lesions were classified as (1) angiographic-visible lesion, (2) barely visible lesion (red-free photography), (3) invisible lesion and respectively correlated to the functional (ETDRS best correct visual acuity) and anatomical (OCT-central macular thickness) outcome one-year pos-treatment.
In 93% of 70 eyes that improved 15 or more letters, the lesions were classified as type 1 (n=35) and type 2 (n=30) lesions. On the contrary, in 80 % of 10 eyes loosing 15 or more letters a type 3 lesion was detected. A parallel anatomical correlation was observed, and 87% of 128 eyes that experienced a complete regression of the macular edema presented a type 1 (n=50) or type 2 lesion (n=62).
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