April 2009
Volume 50, Issue 13
ARVO Annual Meeting Abstract  |   April 2009
Optic Neuritis in Children
Author Affiliations & Notes
  • M.-H. Sun
    Chang Gung Memorial Hospital, Kwei-Shan, Taiwan
  • L.-Y. Kao
    Chang Gung Memorial Hospital, Kwei-Shan, Taiwan
  • H.-S. Wang
    Pediatric neurology,
    Chang Gung Memorial Hospital, Kwei-Shan, Taiwan
  • Footnotes
    Commercial Relationships  M.-H. Sun, None; L.-Y. Kao, None; H.-S. Wang, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 283. doi:
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      M.-H. Sun, L.-Y. Kao, H.-S. Wang; Optic Neuritis in Children. Invest. Ophthalmol. Vis. Sci. 2009;50(13):283.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To document the clinical presentation, associated systemic disease, and visual prognosis of pediatric optic neuritis in Chang Gung Memorial Hospital

Methods: : 60 children admitted for acute optic neuropathy were retrospectively reviewed in Chang Gung Memorial Hospital since 1998~2008. Optic neuritis was diagnosed on the basis of patient history, visual loss, relative afferent pupillary defect ( RAPD ) sign, color vision defect, and ancillary test including visual field (VF) and visual evoked potential (VEP) after excluding infectious, trauma, and compressive origin.

Results: : 26 patients with total 42 eyes met the criteria for diagnosis of optic neuritis. Age at onset ranged from 5 years old to 17 years old. There was a female predilection (61.5%). Bilateral involvement was present in 64.5% of patients, disc swelling was present in 57.1% of patients. In view of systemic association, a preceding viral illness was present in 7 patients ( 30.4%). Among these associated systemic diseases, ADEM( acute disseminated encephalomyelitis ) is the most common associated disease. Final visual acuity over 20/40 was present in 23 eyes ( 67.6% ).

Conclusions: : patients with bilateral involvement, disc swelling have more favorable visual outcome. Image study is needed in all children because associated systemic disease such as ADEM is common.

Keywords: optic nerve • clinical (human) or epidemiologic studies: outcomes/complications 

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