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T. C. Moreira, F. C. L. Silva, L. R. Vilela, P. N. Souza, V. N. Souza, J. A. Netto, M. Senf, F. N. Kanadani; Irvine-Gass Syndrome - Fluorescein Angiography vs. Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2009;50(13):351.
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To investigate and compare detection of Cystoid macular edema (CME) by Fluorescein Angiography (FA) and Optical Coherence Tomography (OCT).
34 patients undergoing cataract extraction by phacoemulsification were prospectively enrolled and followed up for 10 weeks postoperatively. In the follow-up period, FA and OCT were done on days 7, 30 and 60 to detect any evidence of CME. Statistical analysis (Chi-square, Z and Fisher's exact tests) was performed using the software statistical R (version 2.6.0, 2007). Both tests were analyzed by 2 retina specialists following the Nagpal M. et al (2001) criteria.
14 male [41.18%] and 20 female [58.82%] patients were enrolled. On day 7, 8 (25,81%) patients showed CME on OCT among 31 patients who showed no evidence of CME on FA. In patients with CME, the variable Central Retina Thickness was elevated in D7 (241.1 micra, p=0,0001) and D30 (247.2 µm, p=0,0236) and close to normal values (214.8 µm, p=0,6855) in D60. There was no statistically significant difference in intraocular pressure on D7 (12.5 ± 1.58 mmHg), D30 (12.2 ± 2.4 mmHg) and D60 (12.3 ± 1.52 mmHg). There was no difference in visual acuity between with and without CME groups.
OCT is a more sensitive test in detection of CME compared to FA in the immediate postoperative period after cataract extraction.
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