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H. Sakai, Y. Nakamura, A. Tomidokoro, A. Iwase, G. Tomita, T. Yamamoto, H. Abe, S. Sawaguchi, M. Araie; Ocular Biometry of Eyes With Occludable Angles in a Population-Based Study: Kumejima Study. Invest. Ophthalmol. Vis. Sci. 2009;50(13):415.
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© ARVO (1962-2015); The Authors (2016-present)
To summarize ocular biometry of eyes with occludable angles in a population-based study and to evaluate the difference among occludable angle categories and normal subjects.
Of all 4632 residents aged 40 years or older in Kumejima Island, a southern rural island of Japan, 3762 (81.2%) participated in the screening examination including static and dynamic gonioscopy and measurements of, refractive error, axial length, central anterior chamber depth, central corneal thickness, and corneal endothelial cell density. Glaucoma and its suspect, or primary angle closure (PAC) and its suspect (PACS) were diagnosed according to the ISGEO classification scheme. All biometric data were obtained in 2449 subjects who had no history of intraocular surgeries, uveitis, or blunt eye trauma.
416 eyes with occludable angles (PACS, PAC, and PACG or its suspect) had older age, hyperopic refraction, short axial length, and shallow anterior chamber depth compared with 2033 normal eyes without occludable angels (P<0.05). PACG patients were older than those with PACS (P=0.011) or PAC (P<0.001). There was no difference in refractive error among PACS, PAC and PACG. Corneal endothelial cell density was significantly lower in PACG patients than the others (normals, PACS and PAC). Area under the curve (AUC) of receiver-operator characteristics (ROC) against gonioscopic diagnosis was highest with central anterior chamber depth (0.864, 95% confidence interval, 0.845-0.884) among the biometric parameters. Sensitivity and specificity of central anterior chamber depth (cut off value 2.92 mm) was 82% and 78%, respectively.
Ocular dimension of eyes with occludable angles in Kumejima study was smaller than those in normal eyes. PACG patients were older and had decreased corneal endothelial cell density.
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