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K. Aung, S. S. Wickremasinghe, G. Makeyeva, L. Robman, R. H. Guymer; The Prevalence of Idiopathic Macular Telangiectasia Type 2 (IMT): The Melbourne Collaborative Cohort Study. Invest. Ophthalmol. Vis. Sci. 2009;50(13):749.
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To determine the prevalence of idiopathic macular telangiectasia type 2 in an Australian population based upon non mydriatic digital fundus photography.
Participants of the Melbourne Collaborative Cohort Study (MCCS), initiated to investigate risk factors for common aging diseases, had non-mydriatic digital macular images taken from both eyes and graded for any macular abnormalities. Prevalence of the features suggestive of idiopathic macular telangiectasia type 2 were assessed.
Macular images from the 17,600 subjects with a mean age of 66.46 years (range 45-85 years) were assessed. Of these images, 34,381 images were gradable (17,204 images of the right eye and 17,177 images of the left eye). Using only the grading features of the macular images taken by the non-mydriatic digital fundus photography, we found 4 subjects with signs consistent with bilateral idiopathic macular telangiectasia type 2 in this population. Based upon the Gass-Blodi staging of this disease all four were determined to be stage 3.
In an Australian population, the prevalence of idiopathic macular telangiectasia type 2 was found to be 0.0227%, or 1 in 4,400 where disease was at least at stage 3.
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