April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Serial Changes of Fundus Autofluorescence Following Verteporfin Photodynamic Therapy in Chronic Central Serous Chorioretinopathy
Author Affiliations & Notes
  • S.-Y. Yu
    Ophthalmology, Kyung Hee University, Seoul, Republic of Korea
  • E.-S. Kim
    Ophthalmology, Kyung Hee University, Seoul, Republic of Korea
  • H.-W. Kwak
    Ophthalmology, Kyung Hee University, Seoul, Republic of Korea
  • Footnotes
    Commercial Relationships  S.-Y. Yu, None; E.-S. Kim, None; H.-W. Kwak, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 769. doi:
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    • Get Citation

      S.-Y. Yu, E.-S. Kim, H.-W. Kwak; Serial Changes of Fundus Autofluorescence Following Verteporfin Photodynamic Therapy in Chronic Central Serous Chorioretinopathy. Invest. Ophthalmol. Vis. Sci. 2009;50(13):769.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : The purpose of this study was to describe the serial changes of fundus autofluorescence (FAF) following photodynamic therapy (PDT) in chronic central serous chorioretinopathy (CSC).

Methods: : Sixteen eyes of 14 patients with chronic CSC were treated with indocyanine green (ICG) guided verteporfin PDT in accordance with TAP protocol. FAF, visual acuity and OCT was performed at 1 week, 1 month, 3 months, 6 months, and 12 months after PDT.

Results: : After one week, hyperautofluorescent granules appeared. And then after 4 weeks, detached retina was flat down. In some chronic cases stippled hyper- and hypo-autofluorescent area appeared. And then after 3 months, hyperautofluorescence of serous detachment decreased and hyperautofluorescent granules resolved. One year after PDT, hypoautofluorescent spot, patch, lobule appeared in PDT area in some chronic cases.

Keywords: clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials • photodynamic therapy • retinal pigment epithelium 
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