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S.-Y. Yu, E.-S. Kim, H.-W. Kwak; Serial Changes of Fundus Autofluorescence Following Verteporfin Photodynamic Therapy in Chronic Central Serous Chorioretinopathy. Invest. Ophthalmol. Vis. Sci. 2009;50(13):769.
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The purpose of this study was to describe the serial changes of fundus autofluorescence (FAF) following photodynamic therapy (PDT) in chronic central serous chorioretinopathy (CSC).
Sixteen eyes of 14 patients with chronic CSC were treated with indocyanine green (ICG) guided verteporfin PDT in accordance with TAP protocol. FAF, visual acuity and OCT was performed at 1 week, 1 month, 3 months, 6 months, and 12 months after PDT.
After one week, hyperautofluorescent granules appeared. And then after 4 weeks, detached retina was flat down. In some chronic cases stippled hyper- and hypo-autofluorescent area appeared. And then after 3 months, hyperautofluorescence of serous detachment decreased and hyperautofluorescent granules resolved. One year after PDT, hypoautofluorescent spot, patch, lobule appeared in PDT area in some chronic cases.
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