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P. Grenga, S. Lupo, S. Salvatore, A. Meduri, E. M. Vingolo; Retinal Sensitivities and Macular Thickness in Patients Affected by Retinitis Pigmentosa, a Microperimetric (MP-1) and SD OCT Study. Invest. Ophthalmol. Vis. Sci. 2009;50(13):986.
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to evaluate the correlation between retinal sensitivities and retinal thickness in patients affected by retinitis pigmentosa (RP), by means of SD OCT an MP-1.
Fifty eyes of 25 patients (mean age 45.7 + 15.4 years) with RP were examined by the spectral domain optical coherence tomography (SD OCT) and the Micro Perimeter-1 (MP-1). All patients were submitted to a complete ophthalmologic examination (BCVA measured on a Snellen chart, biomicroscopy, applanation tonometry, lens status evaluation, ophthalmoscopic fundus examination) ERG, VEP. OCT measurements were obtained by Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany). Microperimetry was performed on all subjects with the automatic fundus-related perimeter (MP-1 Nidek Technologies, Japan.) with a customize grid covering 10° centered onto the fovea.
12 eyes, mean BCVA 0.82 + 0.07, mean foveal thickness 197,86 microns, mean retinal sensitivities 19.27 + 0.87 dB did not present macular abnormalities. 20 eyes presented cystoid macula edema (CME), with a mean visual acuity of 0.56 + 0.16, mean foveal thickness of 316,99 microns and mean retinal sensitivities of 15.94 + 3.6 dB. 8 eyes affected by vitreoretinal traction showed a mean BCVA of 0.5 + 0.2, mean foveal thickness of 248,5 microns and mean retinal sensitivities of 11.8 + 3 dB; 10 eyes with macular thinning and mean BCVA of 0.3 + 0.1, mean foveal thickness of 107,38 microns and mean retinal sensitivities of 10.22 + 3.8 dB.
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