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K. M. Hartzell, A. Ramasubramanian, C. L. Shields, A. Thangappan, J. A. Shields; Outcome of Total Retinal Detachment From Retinoblastoma Treated With Chemoreduction in 71 Eyes. Invest. Ophthalmol. Vis. Sci. 2009;50(13):1690.
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To evaluate the effects of chemoreduction on total retinal detachment with retinoblastoma (Rb)
Retrospective chart review
Of 71 eyes with retinoblastoma and total retinal detachment, 57 (80%) showed complete resolution of subretinal fluid. The average time for complete retinal reattachment was 6.8 months. Tumor control with chemoreduction was achieved in 18 (25%) and 19 (27%) patients required additional external beam radiation therapy, 24 (34%) required enucleation, and 10 (14%) required both. No patient developed metastasis.
Chemoreduction for retinoblastoma with total retinal detachment provides complete resolution of fluid in 80% of cases.
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