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A. Kissner, A. G. Boehm, L. E. Pillunat, E. Spoerl; Effect of Soft Contact Lens Wear on Corneal Biomechanical Properties. Invest. Ophthalmol. Vis. Sci. 2009;50(13):1753.
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To investigate the effect of long-term soft contact lens wear on corneal biomechanical properties.
In a prospective clinical trial 34 eyes of 17 patients with history of daily soft contact lens wear were examined and subdivided in 2 groups: # 1 history of intermediate- term use (2 - 5 years; n=30 eyes) and # 2 history of long-term use (6 - 32 years; n=14 eyes). 34 eyes of 17 healthy patients without a history of contact lens wear served as controls. Contact lenses were removed at least 12 hours prior to examination. Corneal hysteresis (CH) and corneal resistance factor (CRF) were measured by Ocular Response Analyzer (ORA) and central corneal thickness (CCT) by ultrasound pachymetry. As ORA measurements are dependent on IOP and CCT CH and CRF were adjusted according to the formula:CHcorr = CHmeas - (0.2mmHg)x(18 - IOP) + (0.02mmHg)x(540-CCT);CRFcorr = CRFmeas + (0.1mmHg)x(18 - IOP) + (0.02mmHg)x(540-CCT).
Mean period of contact lens wear was 3.14 years in group # 1 and 13.6 years in group # 2. There was no statistically significant difference in CHcorr between all patients (10.53±1.35mmHg) and the control group (10.60±1.19mmHg ) (P=0.387) and no difference in CRFcorr with 11.32±1.75mmHg and 11.53±1.55mmHg (P=0.357), respectively. CHcorr did not differ between group # 1 compared to the control group: 10.38±1.65mmHg vs 10.61±1.19mmHg; P=0.065. Also CRFcorr was not significantly different between group # 1 compared to the control group: 11.13±2.18mmHg vs. 11.53±1.55mmHg; P=0.058. Similar results were found for group # 2. There was no statistically significant difference in CHcorr and CRFcorr compared to the control group (CHcorr 10.64±1.14mmHg vs. 10.61±1.19mmHg; P=0.888 and CRFcorr 11.46±1.42mmHg vs. 11.53±1.55mmHg; P=0.775). CCT was not significantly different between all patients and the control group (552.8±44.2µm and 553.7±34.1µm; P=0.159). Also when looking separately at the patients of group # 1 or # 2, the difference in CCT compared to the controls did not reach statistical significance (P≥0.05).
Long-term soft contact lens wear seems not to alter the corneal biomechanical properties.
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