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A. Garas, M. Tóth, P. Vargha, G. Holló; Repeatability and Influence of Pupil Dilation on Rnfl Measurement With the Optovue Oct in Different Severity of Glaucoma. Invest. Ophthalmol. Vis. Sci. 2009;50(13):2260.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate repeatability (CoV) and influence of pupil dilation on RNFLT measurements with the Optovue OCT (RTVue) in different glaucoma severity.
1 eye of 14 healthy subjects (MD<2dB), 11 glaucoma patients with MD 6-12dB and 12 glaucoma patients with MD>15dB was scanned with RTVue NHM4 scan (software version 3.5) 5 times before and after pupil dilation. Undilated RNFLT repeatability was compared to that calculated from 5 GDx-VCC and 5 ECC measurements obtained on the same eyes in mydriasis.
Pupil diameter changed from 2.5±1.0 mm to 6.1±1.7 mm (paired t-test, p<0.001). Most RNFLT values did not change in mydriasis, and mean difference remained ≤1.47 µm. CoV was <7% for all parameters and did not change due to pupil dilation (Table 1).Repeatability with RTVue OCT was similar to that with GDx-VCC and ECC, but for RNFLT avg it was consistently better than that found with GDx (VCC or ECC or both). A significant trend for decreasing repeatability in increasing disease severity (Jonckheere-Terpstra test, p<0.007) was seen for all parameters (Table 2).
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