April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Repeatability and Influence of Pupil Dilation on Rnfl Measurement With the Optovue Oct in Different Severity of Glaucoma
Author Affiliations & Notes
  • A. Garas
    Department of Ophthalmology,
    Semmelweis University, Budapest, Hungary
  • M. Tóth
    Department of Ophthalmology,
    Semmelweis University, Budapest, Hungary
  • P. Vargha
    Biometry Unit,
    Semmelweis University, Budapest, Hungary
  • G. Holló
    Department of Ophthalmology,
    Semmelweis University, Budapest, Hungary
  • Footnotes
    Commercial Relationships  A. Garas, None; M. Tóth, None; P. Vargha, None; G. Holló, Carl Zeiss Meditec, Inc., F; Optovue, Inc, F.
  • Footnotes
    Support  Hungarian National Health Grant (ETT) 001/2006 (Dr. Holló)
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 2260. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      A. Garas, M. Tóth, P. Vargha, G. Holló; Repeatability and Influence of Pupil Dilation on Rnfl Measurement With the Optovue Oct in Different Severity of Glaucoma. Invest. Ophthalmol. Vis. Sci. 2009;50(13):2260.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : To evaluate repeatability (CoV) and influence of pupil dilation on RNFLT measurements with the Optovue OCT (RTVue) in different glaucoma severity.

Methods: : 1 eye of 14 healthy subjects (MD<2dB), 11 glaucoma patients with MD 6-12dB and 12 glaucoma patients with MD>15dB was scanned with RTVue NHM4 scan (software version 3.5) 5 times before and after pupil dilation. Undilated RNFLT repeatability was compared to that calculated from 5 GDx-VCC and 5 ECC measurements obtained on the same eyes in mydriasis.

Results: : Pupil diameter changed from 2.5±1.0 mm to 6.1±1.7 mm (paired t-test, p<0.001). Most RNFLT values did not change in mydriasis, and mean difference remained ≤1.47 µm. CoV was <7% for all parameters and did not change due to pupil dilation (Table 1).Repeatability with RTVue OCT was similar to that with GDx-VCC and ECC, but for RNFLT avg it was consistently better than that found with GDx (VCC or ECC or both). A significant trend for decreasing repeatability in increasing disease severity (Jonckheere-Terpstra test, p<0.007) was seen for all parameters (Table 2).

Keywords: imaging/image analysis: clinical • nerve fiber layer • optic nerve 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×