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G. Varas, Sr., P. Garcia, M. Luengo, E. F. Maul, E. Castiglione; Identification of the Preoperative Conjunctival Bacterial Flora in Patients Undergoing Phacoemulsification. Invest. Ophthalmol. Vis. Sci. 2009;50(13):2665.
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We describe the nature and sensitivity to antibiotics of the conjunctival flora in the preoperative of patients undergoing phacoemulsification
We prospectively enrolled patients from two different hospitals. We took a swab from the lower fornix and inoculated it into chocolate and blood agar plates according to standardized technique in a seven-day period before phacoemulsification was performed. Patients receiving topical medication were excluded. Cultures were studied for its sensitivity to cefazolin, chloramphenicol, ciprofloxacin, gentamicin, gatifloxacin, moxifloxacin, vancomycin and tobramycin, using minimum inhibitory concentration (MIC) technique.
We collected a total of 100 samples. We obtained positive cultures in 52% of the samples, 18% were positive for more than one agent. The most frequent microorganism obtained was coagulase-negative Staphyloccus accounting for 67% of positive cultures. Antibiotic sensitivity for each antibiotic was: vancomycin 100%; chloramphenicol, cephazolin and tobramycin 98%; moxifloxacin 94.1%; gentamicin 94%; gatifloxacin 88.2% and 86.3% for ciprofloxacin.The MIC 90 were 8, or ug / ml for cephazolin and chloramphenicol; 7.6 ug / ml gentamicin; 4.0 ug / ml for ciprofloxacin, 1.9 ug / bad for gatifloxacin and 0.95 ug / bad for Moxifloxacin.
We found coagulase-negative Staphylococcus was the most prevalent bacteria in the conjunctival flora in accordance to the literature. Ciprofloxacin and the recently introduced gatifloxacin showed the highest percentage of resistance in our population.
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