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H. Gerding, V. Loukopoulos, J. Riese, L. Hefner, C. Meier, Z. Liampa, M. Timmermann; Clinical Results of pp-Vitrectomy With Densiron 68® Heavy Internal Tamponade Used for Primary Surgery in Eyes With Complicated Rhegmatogenous Retinal Detachment and Clinically Significant PVR. Invest. Ophthalmol. Vis. Sci. 2009;50(13):3172.
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To analyze long-term anatomical results, functional outcome and complications in eyes treated with Densiron tamponade during primary surgery.
Densiron was applied in 26 eyes (26 patients, 16 male, median age 61.5, range 13-91 years). Eyes were presenting PVR stage A in 2, B in 6, C1-C3 in 17 cases, and stage D1 in 1 case. 22 of 26 eyes presented a macula-off detachment; 6 of these a partial foveal detachment. None of the eyes received additional buckling during primary surgery. Densiron was removed after a median of 62 days (range 17 to 99). 23 of 26 eyes were supplied with a mildly impressing encircling band at the time of Densiron removal. Mean follow-up was 15.1+/-12.1 months (median 11.3, range 3-43).
Complete primary retinal attachment was achieved in 26/26 eyes. 1 of 26 eyes developed PVR and secondary detachment before removal of Densiron. 3 of 26 eyes developed a redetachment centrally to the encircling band repaired by secondary intervention. At the end of the follow-up all eyes presented with attached retina; in 3 of these a limited retinal detachment anterior to cerclage was observed. LogMar visual acuity improved from a preoperative level of 1.2+/-0.96 (median 0.8) to 0.79+/-0.49 (median 0.72) at 3 months, 0.64+/-0.38 (median 0.64) at 6 months and 0.44+/-0.34 (median 0.3) at 12 months. 16 of 17 phakic eyes developed a secondary cataract (15 of 16 posterior subcapsular) during follow-up. Dispersed Densiron occurred in 10 of 26 eyes in the anterior segment, 1 case presented a gross inverse pseudohypopyon. The majority of eyes (19 of 26) needed local antiglaucomatous medication during or after the period of internal tamponde; 6 of these until the end of the follow-up period. Chronic hypotony occurred in none of the eyes.
Results of this study indicate that Densiron 68® is an effective and safe heavy internal tamponade substance yielding functionally favourable results when applied in primary retinal detachment surgery with inferior retinal defects and PVR.
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