Purchase this article with an account.
F. A. Killian, A. I. Kotsolis, I. D. Ladas, L. A. Yannuzzi; Fluorescein Angiography and Optical Coherence Tomography Concordance for Choroidal Neovascularization in Multifocal Choroidtis. Invest. Ophthalmol. Vis. Sci. 2009;50(13):3290.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To compare the utility of fluorescein angiography (FA) and optical coherence tomography (OCT) as diagnostic adjuncts in evaluating symptomatic patients with choroidal neovascularization (CNV) due to multifocal choroiditis (MFC).
Patients with CNV due to MFC were retrospectively evaluated in a consecutive fashion. Fundus photography, FA, OCT and biomicroscopy were used to establish the diagnosis. Primary outcome measures included CNV classification (type 1 or occult and type 2 or classic) and the associated FA and OCT findings.
Twenty eyes from seventeen patients were included in the study. In 19 eyes (95%) the FA revealed CNV type 2; in one eye (5%) the type of CNV was indeterminate due to a subretinal hemorrhage that covered the lesion. The OCT images revealed a hyperreflectance beneath the neurosensory retina in all eyes but only 53.8% of them revealed evidence of subretinal fluid (SRF) or intraretinal cystic abnormalities.
The CNV in MFC is virtually always type 2 or classic, with vessels beneath the neurosensory retina. Except when blocked by subretinal blood, the neovascularization is clearly demonstrated by FA. In contrast, only 53.8% of these eyes showed clear evidence of actively proliferating neovascularization on OCT. Therefore, eyes suspected of having CNV in MFC should be evaluated with FA.
This PDF is available to Subscribers Only