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J. L. Krah, D. Krimmel, D. Dodwell; Sterile Endophthalmitis Secondary to Intravitreal Triesence (Triamcinolone Acetonide). Invest. Ophthalmol. Vis. Sci. 2009;50(13):3565.
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© ARVO (1962-2015); The Authors (2016-present)
To report the incidence and clinical course of sterile endophthalmitis associated with office-based intravitreal injection of Triesence (triamcinolone acetonide).
This is a retrospective, consecutive, single center case series. All patients received at least one injection of Triesence. Patients were treated with 4-8 mg/ 0.1-0.2ml of intravitreal "preservative free" Triesence. The procedure was performed with sterile gloves, 10% Povidone Iodine prep, a sterile lid speculum and antibiotic drops. Follow-up after each injection was at least 2 months.
A total of 38 injections of intravitreal Triesence were given during the study period. Sterile endophthalmitis developed in 2 patients (5.3%). Both patients experienced a dramatic, painless decrease in pre-treatment Snellen visual acuity (VA) from 20/60 and 20/100 to the Hand Motion level within 24 hours of their injection. A sterile hypopyon with dense vitreous inflammation was observed in both patients. The VA improved to baseline at 2 months after injection in both patients.
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