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M. H. Steppat, A. Boenisch, E. Schmidt, E. Spoerl, A. G. Boehm, L. E. Pillunat; Correlation Between Corneal Thickness, Corneal Diameter and Optic Disc Size in Non-Glaucomatous Eyes. Invest. Ophthalmol. Vis. Sci. 2009;50(13):3685.
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To examine the correlation between corneal thickness, corneal diameter and optic disc size in non-glaucomatous eyes.
In a prospective clinical trial one randomly chosen eye of 252 healthy subjects (median age 42.5, range 16-86y; 59.9% female, 40.1% male) were examined. Before entering the study each patient received an ophthalmologic exam including evaluation of the optic disc. None of the subjects had signs or a history of glaucoma or ocular hypertension. Optic disc size was measured by HRT II, corneal diameter by keratometry (Auto KeratometerKM-500, NIDEK) and central corneal thickness by ultrasound pachymetry. For statistics Pearson’s correlation coefficents were calculated.
Corneal diameter was statistically significant correlated to disc area (P>0.001, R= 0.263). There was no significant correlation between central corneal thickness and corneal diameter (P=0.839) and between corneal thickness and disc area (p=0.370). Age was negatively correlated to corneal diameter (P=0.001, R=-0.213). There was no correlation between age and corneal thickness (P=0.839).
In contrast to earlier studies in glaucoma patients, in our study in non-glaucomatous eyes corneal thickness does not correlate with optic disc diameter. However, we detected a correlation between optic disc diameter and corneal diameter which was not reported yet.
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