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A. Ramasubramanian, C. L. Shields, S. A. Harmon, J. A. Shields; Autofluorescence of Choroidal Hemangioma in 34 Consecutive Eyes. Invest. Ophthalmol. Vis. Sci. 2009;50(13):3687.
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To describe the autofluorescence features of choroidal hemangioma
Standard fundus photography and autofluorescence (AF) photography (580 nm excitation, 695 nm barrier filter) were performed on all patients. Clinical features were correlated with autofluorescence features.
There were 27 eyes with circumscribed choroidal hemangioma (CCH) and 7 eyes with diffuse choroidal hemangioma (DCH). The mean patient age was 53 years for CCH and 15 years for DCH. Intrinsic AF of untreated CCH was generally isoAF (n=7, 58%) and for treated CCH was hypoAF (n=15, 100%). Extrinsic AF of CCH disclosed hyperAF (orange pigment and fresh subretinal fluid) and hypoAF (RPE hyperplasia, fibrous metaplasia, and atrophy). Intrinsic AF of untreated DCH was generally hypoAF (n=2, 67%) and for treated DCH was hypoAF (n=3, 75%). Extrinsic AF of DCH was similar to CCH.
Choroidal hemangioma shows little intrinsic autofluorescence. Overlying orange pigment and fresh subretinal fluid show hyperAF and RPE hyperplasia and atrophy show hypoAF.
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