April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Optical and Geometric Symmetry Between Fellow Corneas
Author Affiliations & Notes
  • O. Touzeau
    Service 5, CHNO des Quinze-Vingts, Paris, France
  • E. Costantini
    Service 5, CHNO des Quinze-Vingts, Paris, France
  • T. Gaujoux
    Service 5, CHNO des Quinze-Vingts, Paris, France
  • E. Basli
    Service 5, CHNO des Quinze-Vingts, Paris, France
  • R. Kopito
    Service 5, CHNO des Quinze-Vingts, Paris, France
  • L. Laroche
    Service 5, CHNO des Quinze-Vingts, Paris, France
  • V. M. Borderie
    Service 5, CHNO des Quinze-Vingts, Paris, France
  • Footnotes
    Commercial Relationships  O. Touzeau, None; E. Costantini, None; T. Gaujoux, None; E. Basli, None; R. Kopito, None; L. Laroche, None; V.M. Borderie, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 5090. doi:
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    • Get Citation

      O. Touzeau, E. Costantini, T. Gaujoux, E. Basli, R. Kopito, L. Laroche, V. M. Borderie; Optical and Geometric Symmetry Between Fellow Corneas. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5090.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To assess symmetry between fellow corneas in a normal population

Methods: : Both corneas of 300 patients were prospectively analyzed by means of Orbscan topography and ultrasonic pachymetry. The enantiomorphism (mirror-image symmetry) of directional data (i.e., astigmatism axis, location of the thinnest point) was quantified by indices which were calculated using rectangular coordinates (x,y).

Results: : Fellow corneas showed no significant differences (p>0.05) and strong correlation (r≥0.90 p<0.001) for pachymetry and for main optical and geometric properties of the anterior corneal surface. Central ultrasonic pachymetry showed the smallest difference between fellow eyes (1.2% or 6.6 µm) and the strongest correlation (r=0.97 p<0.001). The difference between fellow eyes increased with age (r≥0.23 p<0.001) Corneal astigmatism showed higher enantiomorphism than ocular (subjective) astigmatism (difference between mirror symmetry = 17° vs 27° p<0.001). The degree of enantiomorphism of astigmatism increased significantly with the magnitude of astigmatism (r=0.43 p<0.001). Corneal thickness showed a high degree of enantiomorphism: the location of the thinnest point was in the same quadrant for both eyes in 85% of cases. The degree of enantiomorphism of the cornea decreased significantly with age (pachymetry: r=0.44 p<0.001; astigmatism: r=0.21 p<0.001). Posterior corneal data showed weaker correlation with the fellow cornea (r≤0.72 p<0.001) than did the anterior corneal data.

Conclusions: : The human cornea exhibits a high degree of symmetry and enantiomorphism with the fellow eye for the main geometric and optical properties. However, the symmetry between fellow eyes decreases with aging.

Keywords: cornea: clinical science • topography • astigmatism 
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