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R. B. Mets, L. M. Jampol; A Case of Bilateral Diffuse Uveal Melanocytic Proliferation With a Positive Response to Plasmapheresis. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5243.
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to present a case of Bilteral diffuse melanocytic proliferation associated with metastatic renal cell carcinoma, with an excellent visual response to plasmapheresis.
We studied the case of a 72 year old Caucasian male with a recent diagnosis of renal cell carcinoma, metastatic to his lung, and gradual onset of blurred vision in both eyes. Fundus findings were consistent with BDUMP. The patient was treated with plasmapheresis.
Both vision and fundus findings improved with plasmapheresis. There was loss of serous detachments, decrease in orange pigmentation, and increased visibility of underlying pigmented tumors.
Plasmapheresis should be considered as a treatment methodology in patients with visual loss from bilateral diffuse melanocytic proliferation.
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