Purchase this article with an account.
A. C. James, X.-L. Goh, M. Kolic, R. W. Essex, T. Maddess; Objective Pupillographic Multifocal Perimetry for Glaucoma. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5282.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To investigate 4 variants of multifocal pupillographic perimetry using a prototype of the TrueField Analyser, which objectively assesses both visual fields concurrently.
We tested 35 normal and 44 glaucoma subjects. All eyes were examined with HFA achromatic, SWAP and Matrix 24-2 perimetry, Stratus OCT. Visual fields were classified by HFA mean defects: moderate: 6 to 12 dB, severe: >12 dB. Glaucoma subjects had a moderate to severe visual field in at least one eye. All subjects gave informed written consent. Multifocal stimuli of 4 min. duration, divided into 8 segments of 30s, were presented dichoptically with 24 or 44 regions/eye extending to 30o eccentricity. Individual 30s segments were only repeated if more than 15% of the data was lost due to blinks or fixation losses, both automatically monitored in real time. Mean presentation intervals (MPI) per region were 0.25, 1, or 4s. Most subjects were tested twice with each of the 4 stimuli. The background luminance was 10cd/m2 , and the maximum luminance of all stimuli was the same at 290cd/m2. The stimuli were thus not balanced for visual field sensitivity as in our more recent experiments.
The 44 region, 1 MPI stimuli gave the best diagnostic efficiency, providing area under ROC plots for severe fields of 0.92 ± 0.03 (mean ± SE) and for combined moderate and severe fields of 0.80 ± 0.04.
This PDF is available to Subscribers Only