April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Recurrent Disc Hemorrhage Does Not Increase the Rate of Visual Field Progression
Author Affiliations & Notes
  • H. C. Beck
    Ophthalmology, NYU Medical Center, New York City, New York
  • C. G. V. De Moraes
    Ophthalmology, Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York City, New York
  • T. S. Prata
    Ophthalmology, Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York City, New York
  • F. A. Folgar
    Ophthalmology, NYU Medical Center, New York City, New York
  • K. Ahrlich
    Ophthalmology, NYU Medical Center, New York City, New York
  • C. C. Teng
    Ophthalmology, Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York City, New York
  • R. Ritch
    Ophthalmology, Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York City, New York
  • C. Tello
    Ophthalmology, Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York City, New York
  • J. M. Liebmann
    Ophthalmology, Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York City, New York
  • Footnotes
    Commercial Relationships  H.C. Beck, None; C.G.V. De Moraes, None; T.S. Prata, None; F.A. Folgar, None; K. Ahrlich, None; C.C. Teng, None; R. Ritch, None; C. Tello, None; J.M. Liebmann, None.
  • Footnotes
    Support  Edith C. Blum Foundation Fund and the New York Glaucoma Research Institute, NY, NY
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 5835. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      H. C. Beck, C. G. V. De Moraes, T. S. Prata, F. A. Folgar, K. Ahrlich, C. C. Teng, R. Ritch, C. Tello, J. M. Liebmann; Recurrent Disc Hemorrhage Does Not Increase the Rate of Visual Field Progression. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5835.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Methods: : We evaluated disc photographs of glaucoma patients with ≥5 SITA-Standard 24-2 fields in either eye for the presence and location of DH. Group A had patients with one single detected DH in one eye, and Group B had >1 DH detected in the same eye during follow-up. Pointwise linear regression analysis (Progressor®) was used to calculate rates of progression after DH detection. Exclusion criteria included insufficient VFs to create a slope after DH detection and other ocular conditions likely to affect the VF. Patient demographics, ocular characteristics, and systemic conditions and medications were evaluated.

Results: : 56 patients were enrolled (Group A=40, Group B=16). The mean number of VFs following the initial DH was 9.2±4.4, and mean follow up was similar (Group A, 7.3±4.2 vs Group B 7.6±4.1 yrs, p=0.80). Patients with recurrent DH had less baseline VF damage (-2.75±4.0 vs -5.6±5.0 dB, p<0.01). However, the rate of progression was similar (0.86±0.8 (Group A) vs 0.67±1.0 (Group B) dB/yr, p=0.38). When we adjusted the rates of progression to the baseline MD (general linear model), the difference remained not significant (p=0.61). Age (69.3±12.0 vs 68.2±9.9, p=0.68), female gender (70% vs 50%, p=0.30), CCT (544.1±45.6 vs 543.4±56.6 µm, p=0.74), baseline IOP (16.1±4.0 vs 17.6±4.0, p=0.30), mean IOP post-DH (14.7±2.7 vs 15.3±2.3,p=0.48), prevalence of systemic hypertension (52.5% vs 50%, p=0.40), hypercholesterolemia (32.5% vs 21.4%,p=0.21), and use of ASA/anticoagulation (30% vs 35.7%, p=0.70) were not different between groups. Recurrent DH occurred within 2 clock hours of the initial DH in 88% (14/16) of cases, and in the hemifield with less damage in 75% (12/16).

Conclusions: : Recurrent DH does not result in a faster rate of VF progression and occurs more often in eyes with the less VF damage at baseline, corroborating previous findings that hemorrhages are less likely to occur in areas with significant rim loss.Disclosures: None.Support: Edith C. Blum Foundation Fund and the New York Glaucoma Research Institute, NY, NY.

Keywords: optic nerve • clinical (human) or epidemiologic studies: risk factor assessment 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×