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Y. Fukuma, Y. Okazaki, T. Shioiri, Y. Iida, H. Kikuta, M. Shirakashi, K. Yaoeda, H. Abe, K. Ohnuma; Retardation Measurement in Optic Nerve Fiber Layer by Using a Polarization Camera. Invest. Ophthalmol. Vis. Sci. 2009;50(13):6218.
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To quantify the retardation in the optic nerve fiber layer obtained by using a polarization fundus camera. This camera can detect the Stokes Vector and cancel the effect of cornea retardation using a mathematical technique. So, we can quantify the retardation of the optic nerve fiber layer with one camera shot followed by a calculation. The degree of retardation has a strong relationship with the thickness of the optic nerve fiber layer.
The fundus images of twenty normal eyes were obtained by the polarization fundus camera. The retardations of the optic nerve fiber layer around the optic disk were obtained by calculation. Also, the thickness of each optic nerve fiber layer around the optic disk was measured by using OCT. The retardation and the thickness were compared to one another.
We found a good correlation between the retardation and the thickness of the optic nerve fiber layer around the optic disk.
With this simply constructed system and using a mathematical technique, we could calculate the retardation caused only by the optic nerve fiber layer, and we can predict the thickness of the optic nerve fiber layer. This system can be easily implemented in fundus imaging systems. This instrument will improve diagnosis of the retina.
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