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S. Loukovaara, M. Harju, I. Immonen; Macular Blood Flow Velocity Measured by Blue-field Entoptoscopy and Heidelberg Retinal Flowmetry: Comparision of Two Different Techniques in a Group of Type I Diabetic Women During Pregnancy. Invest. Ophthalmol. Vis. Sci. 2007;48(13):127.
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© ARVO (1962-2015); The Authors (2016-present)
To compare macular capillary blood flow velocity measured with psychophysical blue field entoptic simulation (BFS) technique and confocal scanning laser flowmetry in diabetic women during pregnancy
Macular capillary blood flow velocity was measured by blue-field entoptic simulation using an Oculix BFS-2000 V2.1 psychophysical system and confocal scanning laser flowmeter, Heidelberg Retinal Flowmetry (HRF, Heidelberg Engineering, GmbH, Heidelberg, Germany) in the right eyes of 34 Type I diabetic women during the third trimester.
The macular blood flow velocity measured with the BFS technique correlated significantly with both the 50th percentile HRF velocity (r=0.383, p=0.025, n=34, Spearman's nonparametric correlation) and HRF flow (r=0.431, p=0.012, n=33) during the third trimester. However, there was no correlation between the BFS velocity and the 25th, 75th or 90th percentiles of HRF measurements.
BFS is known to be an experimental technique that provides a quantitative measure of flow in the perifoveal capillary network. On the other hand, HRF image reflects quantitative, multispectral, objective and noinvasive measurements, a 2-D projection of a 3-D retinal capillary bed. In our study, it was shown that the BFS measurements are comparable with the 50th percentile HRF flow and velocity.
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