Purchase this article with an account.
S. Morishita, T. Tanabe, M. Hangai, T. Ojima, N. Yoshimura; The Retinal Nerve Fiber Layer Thickness Measurement in Myopic Glaucoma Eyes: The Comparison Among Scanning Laser Polarimetry With Variable Corneal Compensation, Enhanced Corneal Compensation and Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2007;48(13):504.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To determine the feasibility of scanning laser polarimetry (SLP) with variable corneal compensation (GDx-VCC), enhanced corneal compensation (GDx-ECC) and optical coherence tomography (OCT) for the retinal nerve fiber layer (RNFL) thickness evaluation in myopic glaucoma eyes.
Seventy-three moderate myopic glaucoma eyes (spherical equivalent between -3 and -6diopter (D)) and 55 high myopic glaucoma eyes (spherical equivalent greater than -8D) were enrolled. RNFL measurement by GDx-VCC, GDx-ECC, OCT and also the visual field testing with a Humphrey Field Analyzer program 30-2 (HFA) were conducted in all subjects. The differences in RNFL thickness by GDx-VCC, GDx-ECC and OCT and also their association with visual field parameters were analyzed in both myopic groups.
There was no significant difference in HFA mean deviation (MD) between moderate and high myopic eyes (-7.56dB and -8.36dB, respectively. P=0.53). Both GDx-VCC and GDx-ECC derived RNFL thickness in high myopic group showed significantly higher values than those in moderate myopic group (p=0.001, p=0.002, respectively), while OCT-derived values were similar between the two groups (P=0.43). In both moderate and high myopic glaucoma groups, the association of RNFL values with MD HFA in GDx-VCC was poor compared with the association in GDx-ECC or OCT RNFL measurement. (Moderate myopia; GDx-VCC: r=0.198, GDx-ECC: r=0.502, OCT: r=0.573) (High myopia; GDx-VCC: r=0.359, GDx-ECC: r=0.457, OCT: r=0.626)
GDx-ECC and OCT are useful for the RNFL evaluation in myopic glaucoma eyes, and become help to judge progress of glaucoma.
This PDF is available to Subscribers Only