May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Imaging of External Ocular Tissue With Spectral Domain Polarization Sensitive Optical Coherence Tomography
Author Affiliations & Notes
  • B. Baumann
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
  • E. Götzinger
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
  • M. Pircher
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
  • C. K. Hitzenberger
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
  • Footnotes
    Commercial Relationships B. Baumann, None; E. Götzinger, None; M. Pircher, None; C.K. Hitzenberger, None.
  • Footnotes
    Support FWF Grant P16776 HIGHWIRE EXLINK_ID="48:5:1183:1" VALUE="P16776" TYPEGUESS="GEN, PIRDB, SPROT" /HIGHWIRE -N02
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1183. doi:
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    • Get Citation

      B. Baumann, E. Götzinger, M. Pircher, C. K. Hitzenberger; Imaging of External Ocular Tissue With Spectral Domain Polarization Sensitive Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1183.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To demonstrate the ability of spectral domain polarization sensitive optical coherence tomography (OCT) system to record reflectivity and birefringence images of external human ocular tissue in vivo.

Methods:: A novel spectral domain polarization sensitive OCT system was constructed. A super luminescent diode with a center wavelength of 840 nm and a bandwidth of 50 nm was used to illuminate the sample tissue. The new system requires only a single spectrometer CCD camera to record the polarization sensitive spectral domain data. Compared to previous systems, this reduces system complexity and costs. With a rate of 20000 A-lines/s, the tissue parameters on reflectivity, retardation, and optic axis orientation were recorded simultaneously. Polarization sensitive OCT images of external ocular tissue were recorded in the eyes of healthy volunteers.

Results:: Different structures can be identified based on their polarizing properties: the conjunctiva is non-birefringent, the sclera shows moderate birefringence of varying axis orientation. In addition, a highly birefringent layer, probably tendon of the musculus rectus medialis, can be distinguished.

Conclusions:: The use of polarization sensitive OCT reveals details on the polarization properties of the imaged ocular tissue, allowing to differentiate structures that are difficult to distinguish in intensity based images. The benefits of a spectral domain system are the high sensitivity and image acquisition speed.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • optical properties 
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