May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Anterior Chamber Diameter, Pupillary Diameter, and Angle Width
Author Affiliations & Notes
  • J. E. Manns
    Albert Einstein Coll of Med, Bronx, New York
    Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, New York
  • S. Sandler
    Mount Sinai School of Medicine, New York, New York
  • S. Dorairaj
    Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, New York
  • C. Tello
    Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, New York
    New York Medical College, Valhalla, New York
  • R. Ritch
    Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, New York
    New York Medical College, Valhalla, New York
  • J. Liebmann
    Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, New York
    New York University School of Medicine, New York, New York
  • Footnotes
    Commercial Relationships J.E. Manns, None; S. Sandler, None; S. Dorairaj, None; C. Tello, None; R. Ritch, None; J. Liebmann, Heidelberg Engineering, F; Heidelberg Engineering, R.
  • Footnotes
    Support Ephraim and Catherine Gildor Research Fund of the New York Glaucoma Research Institute, New York, NY
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1210. doi:
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    • Get Citation

      J. E. Manns, S. Sandler, S. Dorairaj, C. Tello, R. Ritch, J. Liebmann; Anterior Chamber Diameter, Pupillary Diameter, and Angle Width. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1210.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To determine the relationships between anterior chamber diameter, pupillary diameter and angle width using Slit-lamp Adapted Optical Coherence Tomography (SL-OCT).

Methods:: Subjects with ANA (Shaffer grade ≤2 in all quadrants) underwent SL-OCT under light and dark conditions. Images were analyzed using SL-OCT software, and angle opening distance at 500 microns (AOD 500) in the superior and inferior angles, pupillary diameter (PD), and anterior chamber diameter (ACD) (defined as scleral spur-to-spur distance) were compared. Pearson product moment correlation was used to evaluate correlation of different measured parameters on a correlation matrix.

Results:: Thirty four eyes (34 subjects) were imaged. AOD 500 was significantly less under dark conditions in the superior angle (light: 0.110 ± 0.09 mm, dark: 0.053 ± 0.06 mm, mean difference: 0.057, p <0.001, paired t-Test) and the inferior angle (light: 0.157 ± 0.080, dark: 0.103 ± 0.07, mean difference: 0.054, p <0.001). PD was significantly smaller in light than in dark (p=0.002) and ACD remained unchanged (p=0.836). AOD was larger in eyes with greater ACD (p<0.05, (r2 range 0.10 - 0.28)). In both light and dark conditions, superior and inferior AOD 500 were significantly correlated (p<0.01). Surprisingly, the PD in light and dark conditions did not correlate with AOD in light and dark conditions, nor did the change in AOD from light to dark correlate with the change in PD (all p>0.05).

Conclusions:: SL-OCT demonstrates narrowing of both superior and inferior angles during provocative dark room testing. The change in AOD was not related to ACD, PD under dark or light conditions, or change in PD.

Keywords: anterior chamber • pupil • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
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