May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Optical Coherence Tomography Study of Filtering Blebs After Trabeculectomy With a Fornix Based Conjunctival Flap
Author Affiliations & Notes
  • K. Hirooka, III
    Ophthalmology, Kagawa Univ Faculty of Medicine, Kita-gun, Japan
  • M. Takagishi
    Ophthalmology, Kagawa Univ Faculty of Medicine, Kita-gun, Japan
  • T. Baba
    Ophthalmology, Kagawa Univ Faculty of Medicine, Kita-gun, Japan
  • H. Takenaka
    Ophthalmology, Kagawa Univ Faculty of Medicine, Kita-gun, Japan
  • F. Shiraga
    Ophthalmology, Kagawa Univ Faculty of Medicine, Kita-gun, Japan
  • Footnotes
    Commercial Relationships K. Hirooka, None; M. Takagishi, None; T. Baba, None; H. Takenaka, None; F. Shiraga, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 868. doi:
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      K. Hirooka, III, M. Takagishi, T. Baba, H. Takenaka, F. Shiraga; Optical Coherence Tomography Study of Filtering Blebs After Trabeculectomy With a Fornix Based Conjunctival Flap. Invest. Ophthalmol. Vis. Sci. 2007;48(13):868.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To investigate the relation between filtering bleb function and optical coherence tomography (OCT), and to establish a new classification of filtering blebs on the basis of OCT findings.

Methods:: One year observational case series. Seventy-one eyes of 64 consecutive patients who underwent primary trabeculectomy with mitomycin C (MMC) and a fornix based conjunctival flap. Filtering blebs were examined by using OCT. The surgical success was defined by the following criteria: (A) intraocular pressure (IOP) ≤ 18 mmHg and IOP reduction ≥ 20%; and (B) IOP ≤ 15 mmHg and IOP reduction ≥ 25%. Success rates among classified groups were compared using Kaplan-Meier survival curves and the log-rank test.

Results:: Blebs were classified into three different categories on the basis of the following OCT patterns; diffuse type (30 eyes), layer type (24 eyes) and space type (17 eyes). For criteria A, success rates were 97%, 79%, and 94% (P = 0.07) in diffuse type bleb, layer type bleb, and space type bleb, respectively; while the success rates for criteria B, 97%, 75%, and 94% (P = 0.03) in these type blebs, respectively.

Conclusions:: In trabeculectomy with MMC and a fornix based conjunctival flap, postoperative OCT findings of filtering blebs are significantly associated with success rates when lower IOPs are required.

Keywords: clinical (human) or epidemiologic studies: outcomes/complications • intraocular pressure 
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