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M. Hatanaka, M. Babic, L. M. Alencar, R. M. Vessani, R. Suzuki, R. Susanna, Jr.; Reproducibility of the Modified Diurnal Tension Curve and Water Drinking Test. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1274.
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to verify the reproducibility of the water drinking test (WDT) response and the intraocular pressure (IOP) measurements during the modified daily tension curve (mDTC) in patients with ocular hypertension (OH) or open-angle glaucoma (OAG).
Prospective analysis of 88 eyes of 88 OH or OAG patients submitted to mDTC followed by the WDT in two consecutive days by the same examiners.
Intraclass correlation coefficient (ICC) values for mDTC measurements at 8:00 am, 11:00 am, 14:00 pm and 16:00 pm were 0.80, 0.82, 0.83 and 0.76, respectively. Maximum IOP, Minimum IOP and fluctuation during mDTC presented ICC values of 0.85, 0.83 and 0.60, respectively. IOP peak and IOP fluctuation during WDT presented ICC values of 0.79 and 0.37, respectively. Diurnal fluctuation, calculated as the difference between maximum IOP obtained with the WDT minus the minimum IOP obtained during the mDTC presented an ICC value of 0.84 (all ICC values, p<0.001).
IOP measurements during each time point of the mDTC presented excellent reproducibility as well as minimum IOP values detected by the mDTC and IOP peak during the WDT. The diurnal fluctuation calculated as IOP peak detected by the WDT and minimum IOP detected by the mDTC, also provided excellent reproducibility.
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