May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Tractional Retinal Detachment After Intravitreal Injection of Bevacizumab in Proliferative Diabetic Retinopathy
Author Affiliations & Notes
  • O. Alvarez-Verduzco
    Retina, Hospital Luis Sanchez Bulnes, Coyoacan ., Mexico
    Retina, Hospital Luis Sanches Bulnes, Mexico DF, Mexico
  • M. Torres-Soriano
    Retina, Hospital Luis Sanchez Bulnes, Coyoacan ., Mexico
  • E. Reyna-Castelan
    Retina, Hospital Luis Sanchez Bulnes, Coyoacan ., Mexico
  • M. Hernandez-Rojas
    Retina, Hospital Luis Sanchez Bulnes, Coyoacan ., Mexico
  • J. L. Díaz-Rubio
    Retina, Hospital Luis Sanchez Bulnes, Coyoacan ., Mexico
  • G. García-Aguirre
    Retina, Hospital Luis Sanchez Bulnes, Coyoacan ., Mexico
  • J. L. Guerrero-Naranjo
    Retina, Hospital Luis Sanchez Bulnes, Coyoacan ., Mexico
  • J. M. Jiménez-Sierra
    Retina, Hospital Luis Sanchez Bulnes, Coyoacan ., Mexico
  • H. Quiroz-Mercado
    Retina, Hospital Luis Sanchez Bulnes, Coyoacan ., Mexico
  • Footnotes
    Commercial Relationships O. Alvarez-Verduzco, None; M. Torres-Soriano, None; E. Reyna-Castelan, None; M. Hernandez-Rojas, None; J.L. Díaz-Rubio, None; G. García-Aguirre, None; J.L. Guerrero-Naranjo, None; J.M. Jiménez-Sierra, None; H. Quiroz-Mercado, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1412. doi:
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    • Get Citation

      O. Alvarez-Verduzco, M. Torres-Soriano, E. Reyna-Castelan, M. Hernandez-Rojas, J. L. Díaz-Rubio, G. García-Aguirre, J. L. Guerrero-Naranjo, J. M. Jiménez-Sierra, H. Quiroz-Mercado; Tractional Retinal Detachment After Intravitreal Injection of Bevacizumab in Proliferative Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1412.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To asses the incidence of tractional retinal detachment (TRD) induced by a single dose of intravitreal bevacizumab in patients with proliferative diabetic retinopathy (PDR).

Methods:: Retrospective review of 343 patients with PDR who where treated with intravitreal injection of bevacizumab (2.5mg/0.1ml).

Results:: Five patients (1.45%) presented tractional retinal detachment 1 to 6 weeks (mean 3 weeks) after intravitreal injection. All cases underwent pars plana vitrectomy, removal of all epiretinal fibrovascular membranes, further endolaser panretinal photocoagulation and silicone tamponade.

Conclusions:: Tractional retinal detachment may occur in a short time post intravitreal injection of bevacizumab in patients with proliferative diabetic retinopathy with extense areas of ischemia and fibrovascular proliferations, and may require prompt vitreoretinal surgery.

Keywords: diabetic retinopathy • retina • drug toxicity/drug effects 
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