May 2007
Volume 48, Issue 13
ARVO Annual Meeting Abstract  |   May 2007
Contamination of Bevacizumab (Avastin) Glass Vials
Author Affiliations & Notes
  • A. Barrera
    Retina, APEC, Mexico City, Mexico
  • V. Cubas-Lorenzo
    Retina, APEC, Mexico City, Mexico
  • A. Solis-Vivanco
    Retina, APEC, Mexico City, Mexico
  • H. Quiroz-Mercado
    Retina, APEC, Mexico City, Mexico
  • J. Fromow-Guerra
    Retina, APEC, Mexico City, Mexico
  • J. Guerrero-Naranjo
    Retina, APEC, Mexico City, Mexico
  • Footnotes
    Commercial Relationships A. Barrera, None; V. Cubas-Lorenzo, None; A. Solis-Vivanco, None; H. Quiroz-Mercado, None; J. Fromow-Guerra, None; J. Guerrero-Naranjo, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1749. doi:
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      A. Barrera, V. Cubas-Lorenzo, A. Solis-Vivanco, H. Quiroz-Mercado, J. Fromow-Guerra, J. Guerrero-Naranjo; Contamination of Bevacizumab (Avastin) Glass Vials. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1749.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose:: To evaluate the possible contamination of bevacizumab (Avastin) glass vials in an in-office storage and utilization procedure for syringe preparation for intravitreal treatments

Methods:: We evaluated 11 bevacizumab (Avastin) glass vials used in different times during 1 year of practice. All vials were storage at 4°C and used during one month for intravitreal treatments for various pathologies. Before the aspiration of the bevacizumab for the preparation of the syringe, the top of the vial was cleaned with povidone 10%. After one month of use the vial was storaged at 4°C and not used again. The asses of contamination was done by cultivation using Brain hearth infusion, Blood agar , Chocolate Agar , Stafilococus 110 Agar , Eosine Methilene Blue Agar , Mac’Conkey Agar, during 3 day of cultivation.

Results:: During 3 day of cultivation none growth was determinate.

Conclusions:: Our results suggest that this office procedure of storage and preparation of bevacizumab syringe doses maintains Avastin glass vials free ofcontamination and can be used safetly for long periods of time.

Keywords: bacterial disease • retina 

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