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C. Murata, E. S. Yamazaki, F. Mallmann, M. Avila, M. Campos; Biomechanical Properties in Adenoviral Corneal Opacity. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1859.
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© ARVO (1962-2015); The Authors (2016-present)
Compare ocular Ocular Response Analyzer (ORA) measurements and ultrasound pachymetry in patients with adenoviral corneal opacity with normal corneas.
Cases included a group of patients with chronic central nummuli adenoviral opacity without corticosteroid medication and uncorrected visual acuity (UCVA) < 20/40. Control group was select from refractive surgery candidates with normal corneas. ORA measurements comprised: corneal compensated intraocular pressure (IOPcc), Goldman correlated IOP measure (IOPg), corneal hysteresis (CH), corneal resistance factor (CRF). Corneal central thickness (CCT) was assed by ultrasound pachymetry (20 MHz). The measurements were done by two independent observers and statistical analysis was performed with level of significance of 0,05.
The adenoviral group consisted of 25 eyes (18 patients), 10 women (55,5%), age 40 +/- 15.6 years old (range 18-65). The control group included 142 eyes (71patients), 51 women (71.8%), age 32.4+/-8.3 years old (range 21-56). Mean corneal central thickness was 512.5+/-39.6 micron (µm) in adenoviral group and 554.6+/-28.9 in control group (p < 0,001). ORA measurements in adenoviral group and control group were, respectively: IOPcc 15.2+/-3.6 and 16.8+/-3.4 mmHg (p = 0,096), IOPg were 13.5+/-2.9 and 16.2+/-3.5 mmHg (p = 0,001), CH were 9.1 +/-1.9 and 11.2+/-11.1 (p = 0,030), CRF were 9.5+/-2.2 and 10.5 +/- 1.5 (p = 0,001).
Differences were observed in ORA measurements and CCT between patients with adenoviral corneal opacity and normal cornea patients. The corneal central thickness, intraocular pressure, CH and CRF values tend to be lower in the adenoviral group.
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