May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Preliminary Outcomes of Endoscopic Vitrectomy for Exchange of Seoul-Type Keratoprosthesis in Rabbit Model
Author Affiliations & Notes
  • S. Lee
    Ophthalmology, Seoul National Univ, Seoul, Republic of Korea
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
  • M. Kim
    Ophthalmology, Seoul National Univ, Seoul, Republic of Korea
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
  • J. Heo
    Ophthalmology, Seoul National Univ, Seoul, Republic of Korea
    Department of Ophthalmology, Seoul Municipal Boramae Hospital, Seoul, Republic of Korea
  • S. Ahn
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
  • J. Ko
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
  • H. Lee
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
  • M. Shin
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
  • M. Lee
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
    Loeys Co., Ltd., Pyeongchang, Gangwon, Republic of Korea
  • W. Wee
    Ophthalmology, Seoul National Univ, Seoul, Republic of Korea
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
  • J. Lee
    Ophthalmology, Seoul National Univ, Seoul, Republic of Korea
    Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Republic of Korea
  • Footnotes
    Commercial Relationships S. Lee, None; M. Kim, None; J. Heo, None; S. Ahn, None; J. Ko, None; H. Lee, None; M. Shin, None; M. Lee, Loeys Co., Ltd., P; W. Wee, None; J. Lee, None.
  • Footnotes
    Support SNUH research fund 03-2006-016-0
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1890. doi:
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      S. Lee, M. Kim, J. Heo, S. Ahn, J. Ko, H. Lee, M. Shin, M. Lee, W. Wee, J. Lee; Preliminary Outcomes of Endoscopic Vitrectomy for Exchange of Seoul-Type Keratoprosthesis in Rabbit Model. Invest. Ophthalmol. Vis. Sci. 2007;48(13):1890.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: Long cylinder of Seoul-type keratoprosthesis (S-KPro) limits adequate views for vitrectomy. It limits the management of retinal detachment after exchange of S-KPro. We investigated the usefulness of endoscopic vitrectomy in exchange of S-KPro.

Methods:: This study was approved by the Institutional Animal Care and Use Committee of the Seoul National University Hospital, and also performed according to ARVO Statement for the Use of Animals in Ophthalmic and Vision Research. 6 S-KPro implanted rabbit eyes for 4 weeks were enrolled for exchange of S-KPro. S-KPros were re-implanted in 3 eyes which had undergone conventional vitrectomy using Eckardt temporary keratoprosthesis after removal of previously installed S-KPro. Other three eyes underwent vitrectomy using endoscopic system(E2 MicroProbeTM, EndoOptics®, USA) prior to SKPro removal and then S-KPro re-implanted. All eyes were evaluated with slit-lamp and ultrasonography weekly.

Results:: Vitreous traction and adhesive membranes surrounding the prolene haptics in ora serrata were found and were precisely excised through the endoscopic view. Two eyes with endoscopic vitrectomy show the retina has been flat till mean follow-up of 10 weeks, but 1 eye developed superiorly localized retinal detachment immediately after exchange because of a preexisting silent hole, but did not progressed for 4 weeks. No anterior segment complication nor endophthalmitis was developed during the follow up period. While, total retinal detachment was developed immediately after exchange of S-KPro in all 3 conventional vitrectomized eyes using Eckardt temporary keratoprosthesis.

Conclusions:: Endoscopic vitrectomy might be helpful to exchange S-KPro safely by removing traction near the ora serrata successfully.

Keywords: keratoprostheses • vitreoretinal surgery • retinal detachment 
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