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S. B. Barone, M. Banitt, P. M. T. Garcia, R. B. Rosen, A. Bertolucci; Precise Imaging Documentation of Scotomata Secondary to Acute Zonal Occult Outer Retinopathy. Invest. Ophthalmol. Vis. Sci. 2007;48(13):2613.
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To report precise imaging documentation through Scanning Laser Ophthalmoscopy-Optical Coherence Tomography (SLO-OCT) of outer retina/RPE segment abnormalities that correlate with electrophysiologic and microperimetric findings as well as the anatomy of the scotomata in a patient with acute zonal occult outer retinopathy (AZOOR).
A 23-year-old woman presented with areas of fogginess in the temporal visual field in both eyes. They are described as three discrete areas paracentrally in the right eye and a C-shaped area in the left. She experienced these symptoms acutely following a viral illness two months prior. Her visual acuity was 20/25 in the right eye and 20/15 in the left. Ophthalmoscopic exam of the anterior segment and fundus was within normal limits in both eyes. SLO-OCT imaging was performed on both eyes as was 10-2 Humphrey visual field (HVF) analysis and multifocal electroretinography (mfERG).
SLO-OCT showed areas of decreased reflectivity that were localized in the outer retina/RPE segment: three paracentral areas in the right eye and a C-shaped one in the left. Temporal scotomata, left eye worse than right, are displayed in the HVF and mfERG shows reduced amplitudes in the nasal macula also with the left eye being more affected than the right.
The patient very precisely describes the scotomata evident in the HVF and OCT findings replicate the anatomy of her symptoms. The mfERG adds that this part of the retina has reduced function. This seems to represent an AZOOR case with precise imaging documentation.
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