May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Clinical Application of High-Speed Swept-Source Three Dimensional Optical Coherence Tomography for Analyzing Anterior Eye Segments After Glaucoma Surgery
Author Affiliations & Notes
  • K. Kawana
    University of Tsukuba, Tsukuba, Japan
    Department of Ophthalmology, Institute of Clinical Medicine,
  • T. Oshika
    University of Tsukuba, Tsukuba, Japan
    Department of Ophthalmology, Institute of Clinical Medicine,
  • M. Miura
    University of Tsukuba, Tsukuba, Japan
    Computational Optics Group, Institute of Applied Physics,
    Department of Ophthalmology, Kasumigaura Hospital, Tokyo Medical University, Ami, Japan
  • T. Yatagai
    University of Tsukuba, Tsukuba, Japan
    Computational Optics Group, Institute of Applied Physics,
  • Y. Yasuno
    University of Tsukuba, Tsukuba, Japan
    Computational Optics Group, Institute of Applied Physics,
  • Footnotes
    Commercial Relationships K. Kawana, None; T. Oshika, None; M. Miura, None; T. Yatagai, None; Y. Yasuno, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2875. doi:
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      K. Kawana, T. Oshika, M. Miura, T. Yatagai, Y. Yasuno; Clinical Application of High-Speed Swept-Source Three Dimensional Optical Coherence Tomography for Analyzing Anterior Eye Segments After Glaucoma Surgery. Invest. Ophthalmol. Vis. Sci. 2007;48(13):2875.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To evaluate high-speed three dimensional swept-source optical coherence tomography (SS-OCT) in evaluating anterior segment structures of eyes after trabeculectomy, trabeculotomy and laser iridotomy.

Methods:: Three dimensional SS-OCT using 1.3 µm light source was developed in Computational Optics Group, University of Tsukuba. A scan rate is 20,000/sec and axial resolution is 7.5 µm in tissute. In contrast to quasi three-dimensional measurement methods, e.g., Pentacam (Oculus, Wetzlar, Germany) or Visante OCT (Carl Zeiss Meditec, Dublin, CA), this OCT acquires full three-dimensional dataset contains 40,000 A-lines/volume with the acquisition time of 2 seconds. The system can obtain two and three dimensional images of the anterior segment. Eyes after trabeculectomy, trabeculotomy and laser iridotomy were analyzed using SS-OCT.

Results:: Three dimensional images of anterior segment structures including conjunctiva, bleb, cornea, sclera, iris, iris root, angle recess, pars plicata of the ciliary body were clearly visualized. Especially three dimensional extent of intraconjunctival fluid space which corresponds to the pathway of the aqueous fluid in the bleb was acquired. The volume of fluid filled space in the bleb was 1.10 mm3. The irregularity of the angle was detected in an eye having trabeculotomy. The position of trabeculotomy was 0.23 mm apart from the angle recess. The laser iridotomy volume in the iris was 0.18 mm3 by volume rendering technique.

Conclusions:: Clear images of the anterior segment structures such as a fluid-filled space of the bleb, angle recess of the eye after trabeculotomy and iridial space after laser iridotomy were obtained by SS-OCT. Precise biometry after glaucoma surgeries was performed. Non-invasive analysis using SS-OCT is useful in evaluating anterior eye structures even immediately after trabeculectomy, trabeculotomy and laser iridotomy.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • anterior segment • imaging/image analysis: clinical 
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