May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Nonlinear ERG Components Are Selectively Reduced in Serous Retinal Detachment With Normal Visual Acuity
Author Affiliations & Notes
  • Y. Shimada
    Ophthalmology, Saitama Medical University, Moroyama Iruma, Japan
  • D. Imai
    Ophthalmology, Saitama Medical University, Moroyama Iruma, Japan
  • Y. Ota
    Ophthalmology, Saitama Medical University, Moroyama Iruma, Japan
  • K. Murayama
    Ophthalmology, Saitama Medical University, Moroyama Iruma, Japan
  • S. Yoneya
    Ophthalmology, Saitama Medical University, Moroyama Iruma, Japan
  • Footnotes
    Commercial Relationships Y. Shimada, None; D. Imai, None; Y. Ota, None; K. Murayama, None; S. Yoneya, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2898. doi:
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      Y. Shimada, D. Imai, Y. Ota, K. Murayama, S. Yoneya; Nonlinear ERG Components Are Selectively Reduced in Serous Retinal Detachment With Normal Visual Acuity. Invest. Ophthalmol. Vis. Sci. 2007;48(13):2898.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To investigate functional and morphological changes in serous retinal detachment with normal visual acuity.

Methods:: Seven eyes of 7 patients with serous retinal detachment (SRD) in central serous chorioretinopathy with normal visual acuity, no less than 20/20, were examined. Multifocal electroretinogram (mfERG) in areas of detachment were compared with that in the corresponding retinal areas of 7 age-matched healthy volunteers (controls) and 6 eyes of 6 patients with diabetic macular edema (DME, mean visual acuity 20/30). Parafoveal thickness of sensory retina was measured by optical coherence tomography (OCT).

Results:: The first order kernel of mfERG (K1) in SRD and DME was significantly smaller than controls. The first slice of the second order kernel (K2.1) in SRD was markedly reduced resulting K2.1-to-K1 amplitude ratio in SRD (mean 0.07) was smaller than controls (0.15) and DME (0.11). Retinal thickness was increased in all DME eyes, but there was no difference between controls and SRD.

Conclusions:: In SRD with normal visual acuity, K2.1 is selectively reduced. Miyake et al. (1988) reported that oscillatory potentials (OPs) of focal macular ERG are more deteriorated than a- or b-wave in patients with SRD. Both OPs and K2.1 are nonlinear ERG components and though to reflect inner retinal function. However morphological changes in SRD with normal visual acuity are hardly observed by OCT except the detachment between photoreceptors and pigment epithelium. Nonlinear ERG components can be reduced under the peculiar photoreceptor condition.

Keywords: electroretinography: clinical • retinal detachment 
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