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J. S. Wolffsohn, G. A. Gibson, L. N. Davies; Violet- vs. Blue-Blocking Intraocular Lenses: A Tint Matched Spectacle Lens-Based Study. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3117.
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© ARVO (1962-2015); The Authors (2016-present)
To examine the effect of blue-blocking and violet-blocking IOL filters on human visual function by means of a range of tests.
Eighteen subjects, aged 27.1± 6.7 years, with healthy eyes and without any color vision deficiency were enrolled in the study. Measurements of visual acuity (logMAR), contrast sensitivity (Pelli-Robson), colour discrimination (FM 100-Hue), short-wavelength automated perimetry (SWAP) and reading speed (MNRead) were performed on their right eye. Each subject wore, in turn, three randomised spectacle lenses. Two of these were matched to the light filtering characteristics of the Alcon AcrySof® Natural blue-blocking IOL and the Bausch & Lomb SofPort® with Violet ShieldTM IOL, respectively; the third was a clear lens with UV absorption. Each spectacle lens was worn on three occasions separated by 5 to 7 days.
Visual acuity (p=0.12), contrast sensitivity (p=0.79), reading acuity (p=0.15), critical print size (p=0.48) and SWAP pattern standard deviation (p=0.91) were all comparable between the three lenses. FM 100-Hue results were analysed using Vingrys’ analysis. Total error (p=0.80), scatter index (p=0.95), confusion index (p=0.45) and angle (p=0.17) were similar between the lenses. Mean defect scores for SWAP, however, were significantly higher in the AcrySof tinted lens (-2.08 ± 1.22 dB) compared to the SofPort Violet Shield (-1.41 ± 1.21 dB) and the clear lens (-1.26 ± 1.44 dB), respectively (p=0.02).
The Alcon AcrySof® Natural blue-blocking and the Bausch & Lomb SofPort® with Violet ShieldTM violet-blocking IOL tints were comparable to one another and to a clear control lens for all measures except short-wavelength automated perimetry. Here, the AcrySof tint reduced subjects’ threshold blue light sensitivity and could thus compromise visual function, particularly in night vision conditions.
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