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T. Fujino, Jr., Y. Saitou, N. Hamanaka, A. Takahasi, S. Sakimoto, K. Nakata, Y. Sakamoto, M. Tatebayasi; Posterior Capsule Opacification After Implantation of a Hydrophilic Acrylic Intraocular Lens (IOL) With Double Square Edge and a Hydropholic Acrylic IOL With Posterior Square Edge. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3124.
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© ARVO (1962-2015); The Authors (2016-present)
It has been reported that the hydrophilic acrylic (hydrogel) intraocular lens (IOL) are more strongery associated with the development of posterior capsule opacification (PCO) than hydrophobic acrylic lens. We prospectively evaluated the effect of square posterior edge in preventing PCO by comparing a hydrophilic acrylic IOL with a double square edge IOL(HP60M , Meridian, Baush &Lomb, Rochester,NY)and hydrophobic acrylic IOL with OptiEdge™ (Sensar, AR40e ,Advanced Medical Optics,Santa Ana,CA)
Fifty-four eyes of 27 patients with bilateral age-related cataract scheduled to undergo cataract extraction were included in this comparetive study. All surgeries were performed by two experienced surgeons according to a standardized protocol that included a corneal incision as small as 2.75millimeters, phacoemulsification, and implantation of an HP60M IOL in one eye , and an AR40e IOL in the other eye of each patient. The PCO in these eyes was measured using a Scheimpflug videophotography system (EAS-1000, Nidek,Kamagooli,Aichi) 1, 3, and 6 months after surgery. Scheimpflug slit images were examined for each 4 sections from 0to 135 degrees and the data were expressed in terms of computer compatible tapes(CCT). The average density value was derived from densitometric analysis. The visual acuity was measured and the incidence of neodymium:YAG (Nd:YAG) laser posterior capsulotomy also was recorded.
In eyes implanted with hydrogel HP60M IOL, the degree of PCO averaged 10.32±4.53 CCT at 1 week, 10.32±5.01 CCT at 1 month, 10.97±7.34 CCT at 3 months, 10.39±3.43 CCT at 6months. In eyes with hydrophobic acryl IOL AR40e, it averaged 8.46±3.12 CCT at 1week, 8.31±3.77 CCT at 1month, 8.33±3.27 CCT at 3months, 8.83±2.86 CCT at 6months. There was no significant difference in the progression of PCO between the two groups. (p>0.05) No eyes underwent Nd:YAG capsulotomy in either group by 6 months postoperatively.
Although a longer follow-up period is needed, these results suggest that the HP60M hydrogel hydrogel IOL with a posterior double-square edge is as effective as the AR40e hydrophobic acrylic IOL with OptiEdgeTM in preventing the development of PCO within 6 months postoperatively.
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