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K. Al-Samir, B. Busse, M. Hahn, S. Pressmar, U. Schaudig; Detection of Osteogenesis in Explanted Synthetic Hydroxyapatite-Silicone Orbital Implants Using the Grinding Technique for Two and Three-Dimensional Preparation of Undecalcified Specimens. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3459.
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To investigate the degree of fibrovascular integration and the presence of osteogenesis in the porous hydroxyapatite part of combined silcon hydroxyapatite orbital implants used in the treatment of the postenucleation socket syndrome.
8 consecutive orbital implants were explanted either because of extrusion of the implant or replacement by another implant at a secondary procedure. All implants were prepared using a grinding technique that allows light microscopic, backscattered electron imaging and microanalytic investigations on undecalcified specimen.
Fibrovascular integration was present at various degrees and did not correlate to the presence of osteogenesis in superficial and deep parts of the implant. Fibrovascular ingrowth and osteogenesis was present despite surface extrusion and conjunctival dehiscence.
Osteogenesis can be present within the pores of combined synthetic hydroxyapatite silicone orbital implants despite extrusion through the anterior surface. Osteogenesis and fibrovascular ingrowth therefore cannot be seen as an indicator for long term biointegration.
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