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H. Obata, S. Makino, K. Ishizaki, T. Inoki, N. Ibaraki; The Relation Between Corneal Horizontal Diameter and Ocular Dimensions and Stature in Japanese Adults. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3530.
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To measure corneal horizontal diameter (white-to-white) in Japanese adults and examine the relation between the corneal horizontal diameter and age and gender as well as the relation between corneal horizontal diameter and axial length (AL), mean corneal radius of curvature (CR), anterior chamber depth (ACD), and body height.
The corneal horizontal diameter, AL, CR, and ACD was measured with IOL Master (Carl Zeiss, Germany) in 333 eyes of 333 Japanese volunteers and preoperative adults aged 21-89 years. There were 161 male subjects and 172 female subjects. The relation between corneal horizontal diameter and the parameters was statistically analyzed. To analyze the relation between the corneal diameter and age, the subjects were divided in two age groups: group 1, 21-49 years of age (n=135); group 2, 50-89 years of age (n=198).
The mean corneal diameter was 12.05±0.44mm (±SD). The mean AL, CR, and ACD was 24.10±1.50mm, 7.70±0.28mm, and 3.27±0.47mm, respectively. The mean corneal diameter was 12.17±0.45mm in males and 11.95±0.41mm in females with statistically significant gender difference (p<0.001). The corneal diameter in males was 12.36±0.41mm in group 1 and 12.01±0.42mm in group 2, while the corneal diameter in females was 12.08±0.42mm in group 1 and 11.88±0.39mm in group 2. The corneal diameter was significantly greater in young group of each gender (p<0.001). The simple correlation coefficient between corneal diameter and age, AL, CR, ACD, and height was -0.361, 0.431, 0.491, 0.473, and 0.355, respectively (p<0.005). The partial correlation coefficient between corneal diameter and age, AL, CR, ACD, and height was 0.052, -0.029, 0.407, 0.346, and 0.049, respectively and corneal diameter was closely related to CR and ACD. The following equation was derived by stepwise multiple regression analysis: corneal horizontal diameter=5.640+0.670xCR+0.383xACD.
The corneal horizontal diameter was significantly greater in males than in females, and significantly greater in subjects under 50 years of age than in subjects over 50 years of age. The corneal horizontal diameter was strongly associated to CR and ACD.
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