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K. J. Ramaiya, J. W. Harbour; High Frequency Ultrasonography in the Evaluation of Primary Cysts of the Iris and Ciliary Body. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3605.
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Primary iris cysts have been classified clinically as central, midzonal, or peripheral. The purpose of this study was to re-evaluate this classification in light of contemporary high-frequency anterior ultrasound.
The medical records and ultrasound scans were reviewed on all patients diagnosed with primary cysts of the iris and/or pars plicata at our Ocular Oncology Service who underwent anterior segment 20 MHz ultrasound evaluation. Secondary cysts and pars plana cysts were excluded.
Inclusion criteria for the study were met by 40 patients, including 19 males, and 21 females. The mean age was 47.1 years (range, 9 years to 84 years). Four categories of iris cysts were defined by location: iris stromal (50%), pars plicata (10%), iris angle (10%), and mixed (30%). Five patients had eye complaints on presentation, the remainder were asymptomatic. Pars plicata cysts were more likely to be multiple and to occur in older individuals. After mean follow-up of 2.9 months (range, 1 to 36 months), none of the cysts enlarged, and 2 cysts developed new cysts. Only one of the cysts required therapeutic intervention.
The historical classification of iris cysts based on clinical features requires modification in light of anatomic detail revealed by high-frequency anterior ultrasound. We propose a new anatomic classification.
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