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Y.-J. Chen, H.-K. Kuo, P.-C. Wu; Macular Hole Size and Central Foveal Thickness in Closed Macular Holes. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3695.
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Vitrectomy and membrane peeling have become standard procedures in treatment of idiopathic macular holes. The purpose of this study was to evaluate the relationship of pre-operative and post-operative OCT measurements in cases with idiopathic macular holes.
This study consisted of a retrospective consecutive series of patients who were operated for idiopathic macular hole in our hospital from July 2005 to July 2006. Fourteen eyes with closed macular hole after the initial operation were included. The follow up period was 3 months or more for inclusion in the study. All of the patients underwent pre-operative and post-operative OCT examination of the macular lesion, including pre-operative size of the macular holes (minimum diameter, hole form factor), and post-operative data of the macular hole (the least foveal thickness, central foveal thickness, and central foveal thickness in 1 mm). The best corrected visual acuity (BCVA) was also examined for analysis.
There was a significant negative correlation between the minimum diameter and both the least foveal thickness (p1) and the central foveal thickness (p2) 1 mm in diameter (p1 = 0.002; p2 = 0.001). Post-operative BCVA had significant positive correlation to the pre-operative BCVA with multiple linear regression analysis (p = 0.014).
In cases with smaller minimum diameter of macular hole pre-operatively, they will have the thicker central foveal thickness post-operatively. The pre-operative vision seems to be predictive value in cases with closed macular holes post-operatively.
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