May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Comparison of Human Corneal, Limbal and Bulbar Conjunctival Epithelial Thickness in vivo Using Optical Coherence Tomography
Author Affiliations & Notes
  • Y. Feng
    CCLR, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
  • T. L. Simpson
    CCLR, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
  • Footnotes
    Commercial Relationships Y. Feng, None; T.L. Simpson, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 3872. doi:
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      Y. Feng, T. L. Simpson; Comparison of Human Corneal, Limbal and Bulbar Conjunctival Epithelial Thickness in vivo Using Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3872.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To compare human central corneal, limbal and bulbar conjunctival epithelial thickness in vivo using Optical Coherence Tomography

Methods:: Thirteen subjects participated in this experiment. Two OCT images were taken from central cornea, temporal limbus and bulbar conjunctiva of left eye. Of 100 serial scans of each image, the central 30 scans were analysed.

Results:: The temporal limbal epithelium is the thickest (79.6 ± 7.4µm, mean ± SD) among the three locations and bulbar conjunctival epithelium is the thinnest (44.9 ± 3.4). The central corneal epithelium is in between (54.7 ± 1.9) in terms of thickness. All of the differences are statistically significant (all p < 0.01).

Conclusions:: Optical coherence tomography is a valuable tool for quantifying corneal, limbal and in particular bulbar conjunctival epithelium in vivo.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • conjunctiva • anatomy 
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