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K.-S. Kim, K. Moon; Prediction of Postoperative Visual Outcome and Foveal Thickness According to Preoperative Hole Factors Measured by Optical Coherence Tomography in Idiopathic Macular Holes. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4124.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate whether an factor based on hole configuration by optical coherence tomography (OCT) can be used to predict the postoperative visual outcome in eyes with idiopathic macular hole.
Fourteen eyes of 22 patients who underwent the vitrectomy with internal limiting membrane peeling for idiopathic stage 3 or 4 macular holes were enrolled in this study. The influence of the preoperative height and size of macular holes on the postoperative visual outcome and foveal thickness were evaluated. By calculating the hole prognostic factor (HPF), the eyes with the HPF>0.8 or <0.8 were assigned as group 1 or group 2, respectively. The HPF was defined as value of the sum of both arm lengths from both ends of RPE level corresponding to the thickened macula to the outer plexiform layer on the margin of a macular hole divided by the distance between both RPE points.
In both group 1 and 2, the postoperative VA was improved (p=0.017, P=0.018), and a difference of the improvement level of VA between the two groups was statistically significant (p=0.05). The postoperative foveal thickness in the group 1 was thicker than the group 2 by 32.15 µm in average, however, it was not statistically significant (p=0.361). There was also no significant correlation between the postoperative VA and the postoperative foveal thickness or the symptom duration (P=0.715, P=0.411), respectively.
This study demonstrated that the HPF would be a prognostic factor for postoperative visual outcome in macular hole surgery.
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