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C. Angora, D. Lepore, F. Molle, M. M. Pagliara, R. De Santis, L. Orazi, A. Baldascino, F. Lafranceschina, G. D'Amico, E. Balestrazzi; Fluorescein Angiography in the Management of Coats' Disease Laser Treatment. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4166.
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Coats’ disease is an ocular disorder characterised by retinal vascular abnormalities resulting in formation of teleangiectasias and microaneurisms that lead to massive intraretinal and subretinal exudation, retinal detachment and neovascular glaucoma. It is well known that appropriate laser treatment could deeply natural history of Coats’, also in some advanced form of retinal detachment (with less than 180° involvement). The aim of the study was to evaluate the fluorescein angiographic findings in Coats prior to laser treatment.
starting from Dec‘04 RETCAM digital fluorescein angiography (Massie Lab., Pleasanton, CA) became available for pediatric ophthalmology unit at the Catholic University Hospital in Rome. Since then 4 babies (4 male; mean age 3.9years) underwent laser treatment for unilateral Coats’ disease. In all cases digital fluorescein angiography under general anesthesia was performed. Based on these findings laser was performed on retinal peripheral avascular and more posterior ischemic area.
One baby (14 months of age) had subtotal retinal detachment, the remnants severe retinal exudation. In 1 eye a laser treatment was repeated after 3 months. In 2 eyes with a minimum follow up of 15 months the disease was relatively stable.
fluorescein angiography allow better visualisation of peripheral avascular retina and posterior ischemic areas. These images can useful drive photoablation, thus optimising laser outcomes.
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