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A. H. The, M. Kurli, S. Dorairaj, P. A. Sidoti, C. Tello, R. Ritch; Ultrasound Biomicroscopy in Iridocorneal Endothelial Syndrome. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4327.
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To describe the ultrasound biomicroscopic (UBM) features ineyes with iridocorneal endothelial (ICE) syndrome.
UBM was performed on 10 patients with ICE and on 10 normal subjects.Seven patients had essential iris atrophy (EIA) and 3 patientshad Chandler’s syndrome (CS) (Table 1). Analysis of anteriorchamber depth (ACD) and angle recess area (ARA) was performedwith UBM Pro2000 Software. ARA was defined by the anterior irissurface, corneal endothelium, and a line drawn 750µm anteriorto the scleral spur. Central corneal thickness (CCT) was determinedby UBM.
Central ACD was lower in patients with ICE (mean 2.41 mm ±SD 0.31 mm) as compared to normal subjects (mean 2.62 mm). Peripheralanterior synechiae (PAS) were observed in all patients withICE syndrome. ARA in the quadrant of maximum PAS was 0 in allpatients with ICE. CCT was elevated in patients with CS. A membranousmound was observed in 2 patients with CS in the anterior chamberangle (Figure 1). PAS and a narrow angle were identified inthe fellow eye of one patient with CS. Two patients with EIArevealed PAS characterized by a focal central adherence of theiris to the cornea and an open iridocorneal angle. One patientwith EIA demonstrated a discrete separation of the iris lamellaewith PAS. A solitary cyst was identified in the fellow eye ofthe same patient.
UBM serves as a valuable tool in the assessment of anteriorsegment characteristics in patients with ICE syndrome. UBM iseffective in identifying PAS and iris atrophy in patients withcorneal edema.
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